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Brain volume estimation from post-mortem newborn and fetal MRI.

Orasanu, E; Melbourne, A; Cardoso, MJ; Modat, M; Taylor, AM; Thayyil, S; Ourselin, S; (2014) Brain volume estimation from post-mortem newborn and fetal MRI. Neuroimage Clin , 6 438 - 444. 10.1016/j.nicl.2014.10.007. Green open access

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Abstract

Minimally invasive autopsy using post-mortem magnetic resonance imaging (MRI) is a valid alternative to conventional autopsy in fetuses and infants. Estimation of brain weight is an integral part of autopsy, but manual segmentation of organ volumes on MRI is labor intensive and prone to errors, therefore unsuitable for routine clinical practice. In this paper we aim to show that volumetric measurements of the post-mortem fetal and neonatal brain can be accurately estimated using semi-automatic techniques and a high correlation can be found with the weights measured from conventional autopsy results.

Type: Article
Title: Brain volume estimation from post-mortem newborn and fetal MRI.
Location: Netherlands
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.nicl.2014.10.007
Publisher version: http://dx.doi.org/10.1016/j.nicl.2014.10.007
Language: English
Additional information: © 2014 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/).
Keywords: Autopsy, Brain volumes, CI, confidence interval, CSF, cerebrospinal fluid, Cerebrum, EM, expectation maximization, Fetus, GA, gestational age, GW, gestational weeks, MRI, magnetic resonance imaging, MaRIAS, Magnetic Resonance Imaging Autopsy Study, Newborn, Post-mortem MRI
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Childrens Cardiovascular Disease
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/1455903
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