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Isolation of esophageal stem cells with potential for therapy.

Maghsoudlou, P; Ditchfield, D; Klepacka, DH; Shangaris, P; Urbani, L; Loukogeorgakis, SP; Eaton, S; (2014) Isolation of esophageal stem cells with potential for therapy. Pediatr Surg Int , 30 (12) 1249 - 1256. 10.1007/s00383-014-3615-6. Green open access

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Abstract

Long-gap esophageal atresia represents a significant challenge for pediatric surgeons and current surgical approaches are associated with significant morbidity. A tissue-engineered esophagus, comprising cells seeded onto a scaffold, represents a therapeutic alternative. In this study, we aimed to determine the optimal techniques for isolation and culture of mouse esophageal epithelial cells and to isolate CD34-positive esophageal epithelial stem cells from cadaveric mouse specimens.

Type: Article
Title: Isolation of esophageal stem cells with potential for therapy.
Location: Germany
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s00383-014-3615-6
Publisher version: http://dx.doi.org/10.1007/s00383-014-3615-6
Language: English
Additional information: © The Author(s) 2014 This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept
URI: https://discovery.ucl.ac.uk/id/eprint/1453551
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