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Cardiovascular risk factors among people with severe mental illness in Italy: A cross-sectional comparative study

Clerici, M; Bartoli, F; Carretta, D; Crocamo, C; Bebbington, P; Carra, G; (2014) Cardiovascular risk factors among people with severe mental illness in Italy: A cross-sectional comparative study. General Hospital Psychiatry , 36 (6) pp. 698-702. 10.1016/j.genhosppsych.2014.08.005. Green open access

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Abstract

Objective: This study aimed to explore the prevalence of cardiovascular disease (CVD) risk factors in people with severe mental illness (SMI), estimating its weight on related risks in Southern Europe, an area with distinct dietary traditions. People with SMI may be more likely than general population to have high prevalence of risk factors for CVDs, due to several reasons, including poor health behaviours and psychopharmacological medications. Method: A cross-sectional study has been conducted, comparing inpatients with and without SMI. Univariate and multivariate analyses and logistic regression models have been carried out, exploring the effect of SMI on the prevalence of CVD risk factors. Results Although obesity and hypertriglyceridemia were more prevalent among people with SMI, controlling for relevant confounders in multivariate analyses we could not detect any significant difference. Conclusions: People with SMI may not necessarily have higher CVD risk, as compared with general population. Mediterranean healthy dietary habits, universal health coverage, families providing strong support, all are possible explanations for our findings. Further research is needed, exploring different mechanisms, with more detailed biological and genetics measures.

Type: Article
Title: Cardiovascular risk factors among people with severe mental illness in Italy: A cross-sectional comparative study
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.genhosppsych.2014.08.005
Publisher version: http://doi.org/10.1016/j.genhosppsych.2014.08.005
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Cardiovascular diseases, Mediterranean diet, Mental Disorders, Comorbidity, Risk factors
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > IoN RLW Inst of Neurological Sci
URI: https://discovery.ucl.ac.uk/id/eprint/1448829
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