Natarajan, D;
Cooper, J;
Choudhury, S;
Delalande, JM;
McCann, C;
Howe, SJ;
Thapar, N;
(2014)
Lentiviral labeling of mouse and human enteric nervous system stem cells for regenerative medicine studies.
Neurogastroenterol Motil
, 26
(10)
pp. 1513-1518.
10.1111/nmo.12420.
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Abstract
Reliable methods of labeling human enteric nervous system (ENS) stem cells for use in novel cell replacement therapies for enteric neuropathies are lacking. Here, we explore the possibility of using lentiviral vectors expressing fluorescent reporter genes to transduce, label, and trace mouse and human ENS stem cells following transplantation into mouse gut.
| Type: | Article |
|---|---|
| Title: | Lentiviral labeling of mouse and human enteric nervous system stem cells for regenerative medicine studies. |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1111/nmo.12420 |
| Publisher version: | http://dx.doi.org/10.1111/nmo.12420 |
| Additional information: | © 2014 The Authors. Neurogastroenterology & Motility published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
| Keywords: | Hirschsprung disease, cell replacement therapy, enteric nervous system stem cells, enteric neuropathies, human gut, lentiviral labeling |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Biology and Cancer Dept |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1447461 |
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