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Effects of exercise on central aortic pressure before and after treatment with renin-angiotensin system blockade in patients with hypertension.

Lacy, PS; Brunel, P; Baschiera, F; Botha, J; Williams, B; (2014) Effects of exercise on central aortic pressure before and after treatment with renin-angiotensin system blockade in patients with hypertension. J Renin Angiotensin Aldosterone Syst 10.1177/1470320314538879. (In press). Green open access

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Abstract

Brachial blood pressure increases with exercise and an excessive rise predicts increased cardiovascular risk. Measurement of brachial blood pressure alone may exaggerate the true blood pressure elevation due to exercise-induced change to pressure amplification. Whether blood pressure-lowering treatment modulates pressure amplification during exercise is unknown.

Type: Article
Title: Effects of exercise on central aortic pressure before and after treatment with renin-angiotensin system blockade in patients with hypertension.
Open access status: An open access version is available from UCL Discovery
DOI: 10.1177/1470320314538879
Publisher version: http://dx.doi.org/10.1177/1470320314538879
Language: English
Additional information: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (http://www.uk.sagepub.com/aboutus/openaccess.htm).
Keywords: Hypertension, angiotensin receptor blocker, central aortic blood pressure, direct renin inhibitor, exercise test
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Population Science and Experimental Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/1437209
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