UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Cognitive strategies regulate fictive, but not reward prediction error signals in a sequential investment task.

Gu, X; Kirk, U; Lohrenz, TM; Montague, PR; (2014) Cognitive strategies regulate fictive, but not reward prediction error signals in a sequential investment task. Hum Brain Mapp , 35 (8) 3738 - 3749. 10.1002/hbm.22433. Green open access

[thumbnail of hbm22433.pdf]
Preview
PDF
hbm22433.pdf

Download (665kB)

Abstract

Computational models of reward processing suggest that foregone or fictive outcomes serve as important information sources for learning and augment those generated by experienced rewards (e.g. reward prediction errors). An outstanding question is how these learning signals interact with top-down cognitive influences, such as cognitive reappraisal strategies. Using a sequential investment task and functional magnetic resonance imaging, we show that the reappraisal strategy selectively attenuates the influence of fictive, but not reward prediction error signals on investment behavior; such behavioral effect is accompanied by changes in neural activity and connectivity in the anterior insular cortex, a brain region thought to integrate subjective feelings with high-order cognition. Furthermore, individuals differ in the extent to which their behaviors are driven by fictive errors versus reward prediction errors, and the reappraisal strategy interacts with such individual differences; a finding also accompanied by distinct underlying neural mechanisms. These findings suggest that the variable interaction of cognitive strategies with two important classes of computational learning signals (fictive, reward prediction error) represent one contributing substrate for the variable capacity of individuals to control their behavior based on foregone rewards. These findings also expose important possibilities for understanding the lack of control in addiction based on possibly foregone rewarding outcomes. Hum Brain Mapp 35:3738-3749, 2014. © 2013 The Authors. Human Brain Mapping Published by Wiley Periodicals, Inc.

Type: Article
Title: Cognitive strategies regulate fictive, but not reward prediction error signals in a sequential investment task.
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/hbm.22433
Publisher version: http://dx.doi.org/10.1002/hbm.22433
Language: English
Additional information: © 2013 The Authors. Human Brain Mapping Published by Wiley Periodicals, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. PMCID: PMC4105325
Keywords: decision-making, emotion regulation, fMRI, fictive learning, insula, reappraisal, reward prediction errors
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
URI: https://discovery.ucl.ac.uk/id/eprint/1436958
Downloads since deposit
125Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item