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The Toast plus plus software suite for forward and inverse modeling in optical tomography

Schweiger, M; Arridge, S; (2014) The Toast plus plus software suite for forward and inverse modeling in optical tomography. Journal of Biomedical Optics , 19 (4) , Article 040801. 10.1117/1.JBO.19.4.040801. Green open access

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Abstract

We present the Toast++ open-source software environment for solving the forward and inverse problems in diffuse optical tomography (DOT). The software suite consists of a set of libraries to simulate near-infrared light propagation in highly scattering media with complex boundaries and heterogeneous internal parameter distribution, based on a finite-element solver. Steady-state, time- and frequency-domain data acquisition systems can be modeled. The forward solver is implemented in C++ and supports performance acceleration with parallelization for shared and distributed memory architectures, as well as graphics processing computation. Building on the numerical forward solver, Toast++ contains model-based iterative inverse solvers for reconstructing the volume distribution of absorption and scattering parameters from boundary measurements of light transmission. A range of regularization methods are provided, including the possibility of incorporating prior knowledge of internal structure. The user can link to the Toast++ libraries either directly to compile application programs for DOT, or make use of the included MATLAB and PYTHON bindings to generate script-based solutions. This approach allows rapid prototyping and provides a rich toolset in both environments for debugging, testing, and visualization.

Type: Article
Title: The Toast plus plus software suite for forward and inverse modeling in optical tomography
Open access status: An open access version is available from UCL Discovery
DOI: 10.1117/1.JBO.19.4.040801
Publisher version: http://dx.doi.org/10.1117/1.JBO.19.4.040801
Language: English
Additional information: © The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.
Keywords: diffuse optical tomography, image reconstruction software, computer program, light transport simulation, Toast plus
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/1436636
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