Schweiger, M;
Arridge, S;
(2014)
The Toast plus plus software suite for forward and inverse modeling in optical tomography.
Journal of Biomedical Optics
, 19
(4)
, Article 040801. 10.1117/1.JBO.19.4.040801.
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Abstract
We present the Toast++ open-source software environment for solving the forward and inverse problems in diffuse optical tomography (DOT). The software suite consists of a set of libraries to simulate near-infrared light propagation in highly scattering media with complex boundaries and heterogeneous internal parameter distribution, based on a finite-element solver. Steady-state, time- and frequency-domain data acquisition systems can be modeled. The forward solver is implemented in C++ and supports performance acceleration with parallelization for shared and distributed memory architectures, as well as graphics processing computation. Building on the numerical forward solver, Toast++ contains model-based iterative inverse solvers for reconstructing the volume distribution of absorption and scattering parameters from boundary measurements of light transmission. A range of regularization methods are provided, including the possibility of incorporating prior knowledge of internal structure. The user can link to the Toast++ libraries either directly to compile application programs for DOT, or make use of the included MATLAB and PYTHON bindings to generate script-based solutions. This approach allows rapid prototyping and provides a rich toolset in both environments for debugging, testing, and visualization.
| Type: | Article |
|---|---|
| Title: | The Toast plus plus software suite for forward and inverse modeling in optical tomography |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1117/1.JBO.19.4.040801 |
| Publisher version: | http://dx.doi.org/10.1117/1.JBO.19.4.040801 |
| Language: | English |
| Additional information: | © The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI. |
| Keywords: | diffuse optical tomography, image reconstruction software, computer program, light transport simulation, Toast plus |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1436636 |
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