Matthews, L;
Enzinger, C;
Fazekas, F;
Rovira, A;
Ciccarelli, O;
Dotti, MT;
Filippi, M;
... Palace, J; + view all
(2015)
MRI in Leber's hereditary optic neuropathy: the relationship to multiple sclerosis.
J Neurol Neurosurg Psychiatry
, 86
(5)
537 - 542.
10.1136/jnnp-2014-308186.
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Abstract
Leber's hereditary optic neuropathy (LHON) and a multiple sclerosis (MS)-like illness appear to coexist 50 times more frequently than would be expected by chance. This association of LHON and MS (LMS) raises an important question about whether there could be a common pathophysiological mechanism involving mitochondrial dysfunction.
| Type: | Article |
|---|---|
| Title: | MRI in Leber's hereditary optic neuropathy: the relationship to multiple sclerosis. |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1136/jnnp-2014-308186 |
| Publisher version: | http://dx.doi.org/10.1136/jnnp-2014-308186 |
| Language: | English |
| Additional information: | This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Keywords: | Leber Heredit Optic Atropy, MRI, Multiple Sclerosis, Neurogenetics |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Brain Repair and Rehabilitation UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Neuroinflammation |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1436003 |
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