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Red blood cell transfusion and mortality in trauma patients: risk-stratified analysis of an observational study.

Perel, P; Clayton, T; Altman, DG; Croft, P; Douglas, I; Hemingway, H; Hingorani, A; ... PROGRESS Partnership; + view all (2014) Red blood cell transfusion and mortality in trauma patients: risk-stratified analysis of an observational study. PLoS Med , 11 (6) , Article e1001664. 10.1371/journal.pmed.1001664. Green open access

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Abstract

Haemorrhage is a common cause of death in trauma patients. Although transfusions are extensively used in the care of bleeding trauma patients, there is uncertainty about the balance of risks and benefits and how this balance depends on the baseline risk of death. Our objective was to evaluate the association of red blood cell (RBC) transfusion with mortality according to the predicted risk of death.

Type: Article
Title: Red blood cell transfusion and mortality in trauma patients: risk-stratified analysis of an observational study.
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1371/journal.pmed.1001664
Publisher version: http://dx.doi.org/10.1371/journal.pmed.1001664
Language: English
Additional information: © 2014 Perel et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Health Informatics
URI: https://discovery.ucl.ac.uk/id/eprint/1433177
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