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A complex multimodal activity intervention to reduce the risk of dementia in mild cognitive impairment-ThinkingFit: pilot and feasibility study for a randomized controlled trial.

Dannhauser, TM; Cleverley, M; Whitfield, TJ; Fletcher, BC; Stevens, T; Walker, Z; (2014) A complex multimodal activity intervention to reduce the risk of dementia in mild cognitive impairment-ThinkingFit: pilot and feasibility study for a randomized controlled trial. BMC Psychiatry , 14 (1) , Article 129. 10.1186/1471-244X-14-129. Green open access

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Abstract

Dementia affects 35 million people worldwide and is currently incurable. Many cases may be preventable because regular participation in physical, mental and social leisure activities during middle age is associated with up to 47% dementia risk reduction. However, the majority of middle-aged adults are not active enough. MCI is therefore a clear target for activity interventions aimed at reducing dementia risk. An active lifestyle during middle age reduces dementia risk but it remains to be determined if increased activity reduces dementia risk when MCI is already evident. Before this can be investigated conclusively, complex multimodal activity programmes are required that (1) combine multiple health promoting activities, (2) engage people with MCI, and (3) result in sufficient adherence rates.

Type: Article
Title: A complex multimodal activity intervention to reduce the risk of dementia in mild cognitive impairment-ThinkingFit: pilot and feasibility study for a randomized controlled trial.
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1186/1471-244X-14-129
Publisher version: http://dx.doi.org/10.1186/1471-244X-14-129
Language: English
Additional information: © 2014 Dannhauser et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. PMCID: PMC4037760
Keywords: Mild cognitive impairment; Alzheimer’s dementia; Dementia prevention; Complex activity intervention; Physical activity; Cognitive stimulation; Social stimulation;
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Division of Psychiatry
URI: https://discovery.ucl.ac.uk/id/eprint/1432430
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