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Paneth cell metaplasia in newly diagnosed inflammatory bowel disease in children.

Simmonds, N; Furman, M; Karanika, E; Phillips, A; Bates, AW; (2014) Paneth cell metaplasia in newly diagnosed inflammatory bowel disease in children. BMC Gastroenterol , 14 (1) , Article 93. 10.1186/1471-230X-14-93. Green open access

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Abstract

Paneth cell metaplasia (PCM) is well described in adults but little is known about the distribution of colonic Paneth cells and the occurrence of PCM in a paediatric population. The aim of this study is to determine whether Paneth cell hyperplasia or metaplasia characteristically occurs in the colons of children with newly diagnosed idiopathic inflammatory bowel disease (IBD).

Type: Article
Title: Paneth cell metaplasia in newly diagnosed inflammatory bowel disease in children.
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1186/1471-230X-14-93
Publisher version: http://dx.doi.org/10.1186/1471-230X-14-93
Language: English
Additional information: © 2014 Simmonds et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. PMCID: PMC4037749
Keywords: Paneth cell; Metaplasia; Paediatric; Ulcerative colitis; Crohn’s disease;
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Pathology
URI: https://discovery.ucl.ac.uk/id/eprint/1432367
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