Brady, S;
Squier, W;
Sewry, C;
Hanna, M;
Hilton-Jones, D;
Holton, JL;
(2014)
A retrospective cohort study identifying the principal pathological features useful in the diagnosis of inclusion body myositis.
BMJ Open
, 4
(4)
, Article e004552. 10.1136/bmjopen-2013-004552.
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Abstract
The current pathological diagnostic criteria for sporadic inclusion body myositis (IBM) lack sensitivity. Using immunohistochemical techniques abnormal protein aggregates have been identified in IBM, including some associated with neurodegenerative disorders. Our objective was to investigate the diagnostic utility of a number of markers of protein aggregates together with mitochondrial and inflammatory changes in IBM.
| Type: | Article |
|---|---|
| Title: | A retrospective cohort study identifying the principal pathological features useful in the diagnosis of inclusion body myositis. |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1136/bmjopen-2013-004552 |
| Publisher version: | http://dx.doi.org/10.1136/bmjopen-2013-004552 |
| Language: | English |
| Additional information: | © 2014 by the BMJ Publishing Group Ltd. All rights reserved. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work noncommercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http:// creativecommons.org/licenses/by-nc/3.0/ |
| Keywords: | Neurology |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Department of Neuromuscular Diseases |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1428693 |
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