Latimer, E;
Anderson, G;
Sebire, NJ;
(2014)
Ultrastructural features of neuroblastic tumours in relation to morphological, and molecular findings; a retrospective review study.
BMC Clin Pathol
, 14
(1)
, Article 13. 10.1186/1472-6890-14-13.
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Abstract
Neuroblastoma is the most common solid tumour of infancy and is responsible for 15% of childhood cancer deaths. Presence of amplified MYCN in neuroblastoma is associated with poor prognosis and rapid tumour progression. The aim of this study was to examine and compare the ultrastructural features of high-risk MYCN amplified neuroblastomas, with lower-risk non-MYCN amplified tumours.
| Type: | Article |
|---|---|
| Title: | Ultrastructural features of neuroblastic tumours in relation to morphological, and molecular findings; a retrospective review study. |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1186/1472-6890-14-13 |
| Publisher version: | http://dx.doi.org/10.1186/1472-6890-14-13 |
| Additional information: | © 2014 Latimer et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| Keywords: | Neuroblastoma; Ultrastructure; Electron microscopy; Molecular biology; MYCN; |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Population, Policy and Practice Dept |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1426486 |
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