Brill, SE;
El-Emir, E;
Allinson, JP;
Donaldson, GC;
Nazareth, I;
Wedzicha, JA;
(2014)
Community-based recruitment of patients with COPD into clinical research.
Thorax
, 69
(10)
951 - 952.
10.1136/thoraxjnl-2014-205253.
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Thorax-2014-Brill-951-2.pdf Download (1MB) |
Abstract
Identifying subjects for clinical trials is difficult and the evidence base for recruitment strategies is limited, particularly in the field of COPD. We compared the efficiency and patient characteristics of different community-based recruitment strategies during a non-commercial COPD trial in the UK. Recruiting from general practice COPD registers was less efficient and identified patients with significantly milder disease than recruiting through pulmonary rehabilitation and patient groups. We report our experience and propose that pulmonary rehabilitation and patient groups may represent an enriched pool of COPD patients to recruit into clinical trials.
Type: | Article |
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Title: | Community-based recruitment of patients with COPD into clinical research. |
Location: | England |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1136/thoraxjnl-2014-205253 |
Publisher version: | http://dx.doi.org/10.1136/thoraxjnl-2014-205253 |
Language: | English |
Additional information: | This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/ |
Keywords: | COPD Epidemiology, Pulmonary Rehabilitation, Biomedical Research, General Practice, Great Britain, Humans, Patient Selection, Pulmonary Disease, Chronic Obstructive |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Primary Care and Population Health |
URI: | https://discovery.ucl.ac.uk/id/eprint/1423459 |
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