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Community-based recruitment of patients with COPD into clinical research.

Brill, SE; El-Emir, E; Allinson, JP; Donaldson, GC; Nazareth, I; Wedzicha, JA; (2014) Community-based recruitment of patients with COPD into clinical research. Thorax , 69 (10) 951 - 952. 10.1136/thoraxjnl-2014-205253. Green open access

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Abstract

Identifying subjects for clinical trials is difficult and the evidence base for recruitment strategies is limited, particularly in the field of COPD. We compared the efficiency and patient characteristics of different community-based recruitment strategies during a non-commercial COPD trial in the UK. Recruiting from general practice COPD registers was less efficient and identified patients with significantly milder disease than recruiting through pulmonary rehabilitation and patient groups. We report our experience and propose that pulmonary rehabilitation and patient groups may represent an enriched pool of COPD patients to recruit into clinical trials.

Type: Article
Title: Community-based recruitment of patients with COPD into clinical research.
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1136/thoraxjnl-2014-205253
Publisher version: http://dx.doi.org/10.1136/thoraxjnl-2014-205253
Language: English
Additional information: This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/
Keywords: COPD Epidemiology, Pulmonary Rehabilitation, Biomedical Research, General Practice, Great Britain, Humans, Patient Selection, Pulmonary Disease, Chronic Obstructive
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Primary Care and Population Health
URI: https://discovery.ucl.ac.uk/id/eprint/1423459
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