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Identification of potential serum peptide biomarkers of biliary tract cancer using MALDI MS profiling.

Sandanayake, NS; Camuzeaux, S; Sinclair, J; Blyuss, O; Andreola, F; Chapman, MH; Webster, GJ; ... Pereira, SP; + view all (2014) Identification of potential serum peptide biomarkers of biliary tract cancer using MALDI MS profiling. BMC Clinical Pathology , 14 (1) , Article 7. 10.1186/1472-6890-14-7. Green open access

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Abstract

The aim of this discovery study was the identification of peptide serum biomarkers for detecting biliary tract cancer (BTC) using samples from healthy volunteers and benign cases of biliary disease as control groups. This work was based on the hypothesis that cancer-specific exopeptidase activities in serum can generate cancer-predictive peptide fragments from circulating proteins during coagulation.

Type: Article
Title: Identification of potential serum peptide biomarkers of biliary tract cancer using MALDI MS profiling.
Open access status: An open access version is available from UCL Discovery
DOI: 10.1186/1472-6890-14-7
Publisher version: http://dx.doi.org/10.1186/1472-6890-14-7
Language: English
Additional information: © 2014 Sandanayake et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. PMCID: PMC3923428
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inst for Liver and Digestive Hlth
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health > Womens Cancer
URI: https://discovery.ucl.ac.uk/id/eprint/1422245
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