Patel, B;
Mortensen, M;
Smart, TG;
(2014)
Stoichiometry of δ subunit containing GABAA receptors.
Br J Pharmacol
, 171
(4)
985 - 994.
10.1111/bph.12514.
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Abstract
Although the stoichiometry of the major synaptic αβγ subunit-containing GABAA receptors has consensus support for 2α:2β:1γ, a clear view of the stoichiometry of extrasynaptic receptors containing δ subunits has remained elusive. Here we examine the subunit stoichiometry of recombinant α4β3δ receptors using a reporter mutation and a functional electrophysiological approach.
Type: | Article |
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Title: | Stoichiometry of δ subunit containing GABAA receptors. |
Location: | England |
Open access status: | An open access version is available from UCL Discovery |
DOI: | 10.1111/bph.12514 |
Publisher version: | http://dx.doi.org/10.1111/bph.12514 |
Language: | English |
Additional information: | © 2013 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of The British Pharmacological Society. This is an open access article under the terms of the Creative Commons Attribution 4.0 License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. synapses |
Keywords: | GABAA receptor, extrasynaptic, stoichiometry, δ subunit |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Neuro, Physiology and Pharmacology |
URI: | https://discovery.ucl.ac.uk/id/eprint/1421949 |
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