Pipinikas, CP;
Kiropoulos, TS;
Teixeira, VH;
Brown, JM;
Varanou, A;
Falzon, M;
Capitanio, A;
... Janes, SM; + view all
(2014)
Cell migration leads to spatially distinct but clonally related airway cancer precursors.
Thorax
, 69
548- 557.
10.1136/thoraxjnl-2013-204198.
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Abstract
Squamous cell carcinoma of the lung is a common cancer with 95% mortality at 5 years. These cancers arise from preinvasive lesions, which have a natural history of development progressing through increasing severity of dysplasia to carcinoma in situ (CIS), and in some cases, ending in transformation to invasive carcinoma. Synchronous preinvasive lesions identified at autopsy have been previously shown to be clonally related.
| Type: | Article |
|---|---|
| Title: | Cell migration leads to spatially distinct but clonally related airway cancer precursors |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1136/thoraxjnl-2013-204198 |
| Publisher version: | http://dx.doi.org/10.1136/thoraxjnl-2013-204198 |
| Language: | English |
| Additional information: | This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 3.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/3.0/ |
| Keywords: | Airway Epithelium, Lung Cancer |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Department of Education UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Respiratory Medicine |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1421827 |
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