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Defining the level of evidence for technology adoption in the localized prostate cancer pathway

Valerio, M; El-Shater Bosaily, A; Emberton, M; Ahmed, HU; (2014) Defining the level of evidence for technology adoption in the localized prostate cancer pathway. Urologic Oncology: Seminars and Original Investigations , 32 (6) pp. 924-930. 10.1016/j.urolonc.2013.10.008. Green open access

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Abstract

New technologies in prostate cancer are attempting to change the current prostate cancer pathway by aiming to reduce harms while maintaining the benefits associated with screening, diagnosis, and treatment. In this article, we discuss the optimal evaluation that new technologies should undergo to provide level 1 evidence typically required to change the practice. With this in mind, we focus on feasible and pragmatic trials that could be delivered in a timely fashion by many centers while retaining primary outcomes that focus on clinically meaningful outcomes.

Type: Article
Title: Defining the level of evidence for technology adoption in the localized prostate cancer pathway
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.urolonc.2013.10.008
Publisher version: http://dx.doi.org/10.1016/j.urolonc.2013.10.008
Language: English
Additional information: Copyright © 2016 Elsevier B.V.Article available under CC BY licence http://creativecommons.org/licenses/by/3.0/
Keywords: Focal therapy, Health technology assessment, MRI, Prostate cancer, Targeted biopsy, Trials, Androgen Antagonists, Humans, Image-Guided Biopsy, Male, Prostate, Prostatectomy, Prostatic Neoplasms, Radiotherapy, Reproducibility of Results, Sensitivity and Specificity
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Targeted Intervention
URI: https://discovery.ucl.ac.uk/id/eprint/1419925
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