Cal, PM;
Frade, RF;
Chudasama, V;
Cordeiro, C;
Caddick, S;
Gois, PM;
(2013)
Targeting cancer cells with folic acid-iminoboronate fluorescent conjugates.
Chem Commun (Camb)
, 50
(40)
pp. 5261-5263.
10.1039/c3cc47534d.
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Abstract
Herein we present the synthesis of fluorescent 2-acetylbenzeneboronic acids that undergo B-N promoted conjugation with lysozyme and N-(2-aminoethyl) folic acid (EDA-FA), generating conjugates that are selectively recognized and internalized by cancer cells that over-express folic acid receptors.
| Type: | Article |
|---|---|
| Title: | Targeting cancer cells with folic acid-iminoboronate fluorescent conjugates. |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1039/c3cc47534d |
| Publisher version: | http://dx.doi.org/10.1039/c3cc47534d |
| Additional information: | © The Royal Society of Chemistry 2014. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Chemistry |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1417809 |
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