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Lipid-Bilayer-Spanning DNA Nanopores with a Bifunctional Porphyrin Anchor.

Burns, JR; Göpfrich, K; Wood, JW; Thacker, VV; Stulz, E; Keyser, UF; Howorka, S; (2013) Lipid-Bilayer-Spanning DNA Nanopores with a Bifunctional Porphyrin Anchor. Angew Chem Int Ed Engl , 52 (46) pp. 12069-12072. 10.1002/anie.201305765. Green open access

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Abstract

Holding tight: An artificial membrane nanopore assembled from DNA oligonucleotides carries porphyrin tags (red), which anchor the nanostructure into the lipid bilayer. The porphyrin moieties also act as fluorescent dyes to aid the microscopic visualization of the DNA nanopore.

Type: Article
Title: Lipid-Bilayer-Spanning DNA Nanopores with a Bifunctional Porphyrin Anchor.
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/anie.201305765
Publisher version: http://dx.doi.org/10.1002/anie.201305765
Additional information: © 2013 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Keywords: DNA structures, membranes, nanopores, porphyrins, single-molecule studies
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Chemistry
URI: https://discovery.ucl.ac.uk/id/eprint/1405131
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