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Epidemiology of lifetime fracture prevalence in England: a population study of adults aged 55 years and over

Scholes, S; Panesar, S; Shelton., NJ; Francis, R; Mirza, S; Mindell, J; Donaldson, L; (2014) Epidemiology of lifetime fracture prevalence in England: a population study of adults aged 55 years and over. Age and Ageing , 43 (2) pp. 234-240. 10.1093/ageing/aft167. Green open access

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Abstract

Background: Fractures remain a substantial public health problem but epidemiological studies using survey data are sparse. This study explores the association between lifetime fracture prevalence and socio-demographic factors, health behaviours and health conditions. Methods: Fracture prevalence was calculated using a combined dataset of annual, nationally representative health surveys in England (2002-2007) containing 24,725 adults aged 55 years and over. Odds of reporting any fracture was estimated separately for each gender using logistic regression. Results: Fracture prevalence was higher in men than women (49% and 40%, respectively). In men, factors having a significant independent association with fracture included being a former regular smoker [OR: 1.18 (1.06 to 1.31)], having a limiting long-standing illness [OR: 1.47 (1.31 to 1.66)] and consuming >8 units of alcohol on the heaviest drinking day in the past week [OR: 1.65 (1.37 to 1.98)]. In women, significant factors included being separated/divorced [OR: 1.30 (1.10 to 1.55)], having a GHQ-12 score of 4+ [OR: 1.59 (1.27 to 2.00)], consuming >6 units of alcohol in the past week [OR: 2.07 (1.28 to 3.35)] and being obese [OR: 1.25 (1.03 to 1.51)]. Conclusion: A range of socio-demographic, health behaviour and health conditions, known to increase the risk of chronic disease and premature death, are also associated with fracture occurrence, probably involving the aetiological pathways of poor bone health and fall-related trauma. Keywords: lifetime fracture prevalence; fracture sites; risk factors; logistic regression; respondent recall

Type: Article
Title: Epidemiology of lifetime fracture prevalence in England: a population study of adults aged 55 years and over
Open access status: An open access version is available from UCL Discovery
DOI: 10.1093/ageing/aft167
Publisher version: http://dx.doi.org/10.1093/ageing/aft167
Language: English
Additional information: © The Author 2013. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. This is a pre-copyedited, author-produced PDF of an article accepted for publication in Age and Ageing following peer review. The definitive publisher-authenticated version: First published online: November 14, 2013 is available online at: doi: 10.1093/ageing/aft167
Keywords: Fracture sites, lifetime fracture prevalence, logistic regression, respondent recall, risk factors, older people
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health
URI: https://discovery.ucl.ac.uk/id/eprint/1404001
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