Schapira, AH;
(2013)
Recent developments in biomarkers in Parkinson disease.
Curr Opin Neurol
, 26
(4)
395 - 400.
10.1097/WCO.0b013e3283633741.
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Abstract
Parkinson disease is the second most common neurodegenerative disease after Alzheimer disease, and current demographic trends indicate a life-time risk approaching 4% and predict a doubling of prevalence by 2030. Strategies are being developed to apply recent advances in our understanding of the cause of Parkinson disease to the development of biomarkers that will enable the identification of at-risk individuals, enable early diagnosis and reflect the progression of disease. The latter will be particularly important for the testing of disease-modifying therapies. This review summarizes recent advances in Parkinson disease biomarker development.
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