Konstantinidis, AC;
Zheng, Y;
Olivo, A;
Bliznakova, K;
Yip, M;
Anaxagoras, T;
Wells, K;
... Speller, RD; + view all
(2012)
Evaluation of a Novel Wafer-Scale CMOS APS XRay Detector for Use in Mammography.
In:
Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2012 IEEE.
(pp. 3254 - 3260).
IEEE: Piscataway, NJ, USA.
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Abstract
The most important factors that affect the image quality are contrast, spatial resolution and noise. These factors and their relationship are quantitatively described by the Contrast-to-Noise Ratio (CNR), Signal-to-Noise Ratio (SNR), Modulation Transfer Function (MTF), Noise Power Spectrum (NPS) and Detective Quantum Efficiency (DQE) parameters. The combination of SNR, MTF and NPS determines the DQE, which represents the ability to visualize object details of a certain size and contrast at a given dose. In this study the performance of a novel large area Complementary Metal-Oxide-Semiconductor (CMOS) Active Pixel Sensor (APS) X-ray detector, called DynAMITe (Dynamic range Adjustable for Medical Imaging Technology), was investigated and compared to other three digital mammography systems (namely a) Large Area Sensor (LAS), b) Hamamatsu C9732DK, and c) Anrad SMAM), in terms of physical characteristics and evaluation of the image quality. DynAMITe detector consists of two geometrically superimposed grids: a) 2560 x 2624 pixels at 50 11m pitch, named Sub-Pixels (SP camera) and b) 1280 x 1312 pixels at 100 11m pitch, named Pixels (P camera). The X-ray performance evaluation of DynAMITe SP detector demonstrated high DQE results (0.58 to 0.64 at 0.5 Ip/mm). Image simulation based on the X-ray performance of the detectors was used to predict and compare the mammographic image quality using ideal software phantoms: a) one representing two three dimensional (3-D) breasts of various thickness and glandularity to estimate the CNR between simulated microcalcifications and the background, and b) the CDMAM 3.4 test tool for a contrast-detail analysis of small thickness and low contrast objects. The results show that DynAMITe SP detector results in high CNR and contrast-detail performance.
| Type: | Proceedings paper |
|---|---|
| Title: | Evaluation of a Novel Wafer-Scale CMOS APS XRay Detector for Use in Mammography |
| Event: | 2012 Nuclear Science Symposium, Medical Imaging Conference |
| Location: | Anaheim, California |
| Dates: | 2012-10-29 - 2012-11-03 |
| ISBN: | 978-1-4673-2028-3 |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1109/NSSMIC.2012.6551742 |
| Publisher version: | http://dx.doi.org/10.1109/NSSMIC.2012.6551742 |
| Language: | English |
| Additional information: | © 2012 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works |
| Keywords: | sensors, biomedical equipment, CMOS digital integrated circuits, diagnostic radiography, mammography, noise, phantoms |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1399523 |
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