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Homeostatic synaptic plasticity: from single synapses to neural circuits.

Vitureira, N; Letellier, M; Goda, Y; (2012) Homeostatic synaptic plasticity: from single synapses to neural circuits. Current Opinion in Neurobiology , 22 (3) 516 - 521. 10.1016/j.conb.2011.09.006. Green open access

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Abstract

Homeostatic synaptic plasticity remains an enigmatic form of synaptic plasticity. Increasing interest on the topic has fuelled a surge of recent studies that have identified key molecular players and the signaling pathways involved. However, the new findings also highlight our lack of knowledge concerning some of the basic properties of homeostatic synaptic plasticity. In this review we address how homeostatic mechanisms balance synaptic strengths between the presynaptic and the postsynaptic terminals and across synapses that share the same postsynaptic neuron.

Type: Article
Title: Homeostatic synaptic plasticity: from single synapses to neural circuits.
Location: UK
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.conb.2011.09.006
Publisher version: http://dx.doi.org/10.1016/j.conb.2011.09.006
Language: English
Additional information: This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. PMCID: PMC3378479
Keywords: Animals, Homeostasis, Nerve Net, Neuronal Plasticity, Neurons, Synapses
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/1399234
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