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Dissociating frontal regions that co-lateralize with different ventral occipitotemporal regions during word processing

Seghier, ML; Price, CJ; (2013) Dissociating frontal regions that co-lateralize with different ventral occipitotemporal regions during word processing. Brain & Language , 126 (2) 133 - 140. 10.1016/j.bandl.2013.04.003. Green open access

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Abstract

The ventral occipitotemporal sulcus (vOT) sustains strong interactions with the inferior frontal cortex during word processing. Consequently, activation in both regions co-lateralize towards the same hemisphere in healthy subjects. Because the determinants of lateralisation differ across posterior, middle and anterior vOT subregions, we investigated whether lateralisation in different inferior frontal regions would co-vary with lateralisation in the three different vOT subregions. A whole brain analysis found that, during semantic decisions on written words, laterality covaried in (1) posterior vOT and the precentral gyrus; (2) middle vOT and the pars opercularis, pars triangularis, and supramarginal gyrus; and (3) anterior vOT and the pars orbitalis, middle frontal gyrus and thalamus. These findings increase the spatial resolution of our understanding of how vOT interacts with other brain areas during semantic categorisation on words.

Type: Article
Title: Dissociating frontal regions that co-lateralize with different ventral occipitotemporal regions during word processing
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.bandl.2013.04.003
Publisher version: http://dx.doi.org/10.1016/j.bandl.2013.04.003
Language: English
Additional information: © 2013 Elsevier Inc. All rights reserved. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Imaging Neuroscience
URI: https://discovery.ucl.ac.uk/id/eprint/1396091
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