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Applications of a non-interferometric x-ray phase contrast imaging method with both synchrotron and conventional sources

Endrizzi, M; Diemoz, PC; Munro, PRT; Hagen, CK; Szafraniec, MB; Millard, TP; Zapata, CE; ... Olivo, A; + view all (2013) Applications of a non-interferometric x-ray phase contrast imaging method with both synchrotron and conventional sources. In: Journal of Instrumentation. (pp. C05008-0). IOP: UK. Green open access

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Abstract

We have developed a totally incoherent, non-interferometric x-ray phase contrast imaging (XPCI) method. This is based on the edge illumination (EI) concept developed at the ELETTRA synchrotron in Italy in the late ‘90s. The method was subsequently adapted to the divergent beam generated by a conventional source, by replicating it for every detector line through suitable masks. The method was modelled both with the simplified ray-tracing and with the more rigorous wave-optics approach, and in both cases excellent agreement with the experimental results was found. The wave-optics model enabled assessing the methods’ coherence requirements, showing that they are at least an order of magnitude more relaxed than in other methods, without this having negative consequences on the phase sensitivity. Our masks have large pitches (up to 50 times larger than in grating interferometry, for example), which allows for manufacturing through standard lithography, scalability, cost-effectiveness and easiness to align. When applied to a polychromatic and divergent beam generated by a conventional source, the method enables the detection of strong phase effects also with uncollimated, unapertured sources with focal spots of up to 100 mm, compatible with the state-of-the-art in mammography. When used at synchrotrons, it enables a contrast increase of orders of magnitude over other methods. Robust phase retrieval was proven for both coherent and incoherent sources, and additional advantages are compatibility with high x-ray energies and easy implementation of phase sensitivity in two directions simultaneously. This paper briefly summarizes these achievements and reviews some of the key results.

Type: Proceedings paper
Title: Applications of a non-interferometric x-ray phase contrast imaging method with both synchrotron and conventional sources
Event: 7th MEDICAL APPLICATIONS OF SYNCHROTRON RADIATION WORKSHOP (MASR 2012)
Location: SHANGHAI
Dates: 2012-10-17 - 2012-10-20
Open access status: An open access version is available from UCL Discovery
DOI: 10.1088/1748-0221/8/05/C05008
Publisher version: http://dx.doi.org/10.1088/1748-0221/8/05/C05008
Language: English
Additional information: © 2013 IOP Publishing Ltd and Sissa Medialab srl Open access articles from IOP are published under a creative commons attribution licence or CC-BY Licence. This allows users to re-use the content in any way they like, provided it is accurately attributed. Copyright stays with the agreed copyright owner.
Keywords: Inspection with x-rays, Detection of defects, X-ray radiography and digital radiography, X-ray mammography and scinto- and MRI-mammography
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/1395169
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