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The role of the gastrointestinal tract in phosphate homeostasis in health and chronic kidney disease.

Marks, J; Debnam, ES; Unwin, RJ; (2013) The role of the gastrointestinal tract in phosphate homeostasis in health and chronic kidney disease. Curr Opin Nephrol Hypertens , 22 (4) 481 - 487. 10.1097/MNH.0b013e3283621310. Green open access

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Abstract

For a number of years, there has been increasing interest in the concept of directly targeting intestinal phosphate transport to control hyperphosphatemia in chronic kidney disease. However, progress has been slow due to the paucity of information on the mechanisms involved in intestinal phosphate absorption. This editorial highlights the most recent developments in our understanding of this process and the role of the intestine in the maintenance of phosphate balance.

Type: Article
Title: The role of the gastrointestinal tract in phosphate homeostasis in health and chronic kidney disease.
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1097/MNH.0b013e3283621310
Publisher version: http://dx.doi.org/10.1097/MNH.0b013e3283621310
Language: English
Additional information: © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins. This is an open access article distributed under the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by-nc-nd/4.0.
Keywords: Animals, Food Preservatives, Homeostasis, Humans, Hyperphosphatemia, Intestinal Absorption, Intestines, Mice, Mice, Knockout, Phosphates, Phosphorus, Dietary, Renal Insufficiency, Chronic, Sodium-Phosphate Cotransporter Proteins, Type IIb
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Neuro, Physiology and Pharmacology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/1393792
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