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First genome-wide association study on anxiety-related behaviours in childhood.

Trzaskowski, M; Eley, TC; Davis, OS; Doherty, SJ; Hanscombe, KB; Meaburn, EL; Haworth, CM; ... Plomin, R; + view all (2013) First genome-wide association study on anxiety-related behaviours in childhood. PLoS One , 8 (4) , Article e58676. 10.1371/journal.pone.0058676. Green open access

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Abstract

Twin studies have shown that anxiety in a general population sample of children involves both domain-general and trait-specific genetic effects. For this reason, in an attempt to identify genes responsible for these effects, we investigated domain-general and trait-specific genetic associations in the first genome-wide association (GWA) study on anxiety-related behaviours (ARBs) in childhood.

Type: Article
Title: First genome-wide association study on anxiety-related behaviours in childhood.
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1371/journal.pone.0058676
Publisher version: http://dx.doi.org/10.1371/journal.pone.0058676
Language: English
Additional information: © 2013 Trzaskowski et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Funding: TEDS is supported by a program grant (G0500079) from the U.K. Medical Research Council (MRC), with additional support from the US National Institutes of Health (HD044454; HD046167). Genome-wide genotyping was made possible by grants from the Wellcome Trust Case Control Consortium 2 project (085475/B/08/Z; 085475/Z/08/Z). RP is supported by a Medical Research Council Research Professorship award (G19/2) and a European Advanced Investigator award (295366); O.S.P.D. is supported by a Sir Henry Wellcome Fellowship from the Wellcome Trust (WT088984); C.M.A.H. is supported by a research fellowship from the British Academy. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
URI: https://discovery.ucl.ac.uk/id/eprint/1391239
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