Briggs, D;
Morgan, JE;
(2013)
Recent progress in satellite cell/myoblast engraftment – relevance for therapy.
FEBS Journal
, 280
(17)
pp. 4281-4293.
10.1111/febs.12273.
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Abstract
There is currently no cure for muscular dystrophies, although several promising strategies are in basic and clinical research. One such strategy is cell transplantation with satellite cells (or their myoblast progeny) to repair damaged muscle and provide dystrophin protein with the aim of preventing subsequent myofibre degeneration and repopulating the stem cell niche for future use. The present review aims to cover recent advances in satellite cell/myoblast therapy and to discuss the challenges that remain for it to become a realistic therapy.
| Type: | Article |
|---|---|
| Title: | Recent progress in satellite cell/myoblast engraftment – relevance for therapy |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1111/febs.12273 |
| Publisher version: | http://dx.doi.org/10.1111/febs.12273 |
| Language: | English |
| Additional information: | This work is licensed under the Creative Commons Attribution License, Attribution 3.0 Unported (CC BY 3.0) http://creativecommons.org/licenses/by/3.0/ which permits unrestricted use, distribution, and reproduction in any medium. However, you must attribute the work to the author (but not in any way that suggests that they endorse you or your use of the work). |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Neurosciences Dept |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1390992 |
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