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The cell biology of receptor-mediated virus entry.

Grove, J; Marsh, M; (2011) The cell biology of receptor-mediated virus entry. Journal of Cell Biology , 195 (7) 1071 - 1082. 10.1083/jcb.201108131. Green open access

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Abstract

The cell imposes multiple barriers to virus entry. However, viruses exploit fundamental cellular processes to gain entry to cells and deliver their genetic cargo. Virus entry pathways are largely defined by the interactions between virus particles and their receptors at the cell surface. These interactions determine the mechanisms of virus attachment, uptake, intracellular trafficking, and, ultimately, penetration to the cytosol. Elucidating the complex interplay between viruses and their receptors is necessary for a full understanding of how these remarkable agents invade their cellular hosts.

Type: Article
Title: The cell biology of receptor-mediated virus entry.
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1083/jcb.201108131
Publisher version: http://dx.doi.org/10.1083/jcb.201108131
Language: English
Additional information: PMCID: PMC3246895
Keywords: Animals, Cell Biology, Humans, Receptors, Virus, Viruses
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Lab for Molecular Cell Bio MRC-UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity
URI: https://discovery.ucl.ac.uk/id/eprint/1389084
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