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Post-operative recurrent trachomatous trichiasis is associated with increased conjunctival expression of S100A7 (psoriasin).

Burton, MJ; Rajak, SN; Ramadhani, A; Weiss, HA; Habtamu, E; Abera, B; Emerson, PM; ... Bailey, RL; + view all (2012) Post-operative recurrent trachomatous trichiasis is associated with increased conjunctival expression of S100A7 (psoriasin). PLoS Neglected Tropical Diseases , 6 (12) , Article e1985. 10.1371/journal.pntd.0001985. Green open access

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Abstract

Surgery for trachomatous trichiasis (TT) is a key component of the SAFE Strategy for trachoma control. Unfortunately, recurrent TT following surgery is common, probably due to various surgical and disease factors. To develop strategies to reduce recurrence rates it is necessary to understand its pathological basis. In this study we investigated the relationship between recurrent trichiasis and the expression of various cytokines and fibrogenic genes during a two-year follow-up period.

Type: Article
Title: Post-operative recurrent trachomatous trichiasis is associated with increased conjunctival expression of S100A7 (psoriasin).
Location: US
Open access status: An open access version is available from UCL Discovery
DOI: 10.1371/journal.pntd.0001985
Publisher version: http://dx.doi.org/10.1371/journal.pntd.0001985
Language: English
Additional information: © 2012 Burton et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. PMCID: PMC3527350
Keywords: Adolescent, Adult, Aged, Aged, 80 and over, Biological Markers, Case-Control Studies, Female, Gene Expression, Humans, Male, Middle Aged, Prognosis, Recurrence, S100 Proteins, Trachoma, Trichiasis, Young Adult
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
URI: https://discovery.ucl.ac.uk/id/eprint/1386401
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