UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Self-Navigated Tissue Phase Mapping Using a Golden-Angle Spiral Acquisition-Proof of Concept in Patients with Pulmonary Hypertension

Steeden, JA; Knight, DS; Bali, S; Atkinson, D; Taylor, AM; Muthurangu, V; (2013) Self-Navigated Tissue Phase Mapping Using a Golden-Angle Spiral Acquisition-Proof of Concept in Patients with Pulmonary Hypertension. Magnetic Resonance in Medicine , 71 (1) pp. 145-155. 10.1002/mrm.24646. Green open access

[img]
Preview
Text
Atkinson_MRM-12-13625_Revision_Clean.pdf - Accepted version

Download (323kB) | Preview
[img]
Preview
Image
Atkinson_Figure1.tif - Accepted version

Download (19MB) | Preview
[img]
Preview
Image
Atkinson_Figure2.tif - Accepted version

Download (26MB) | Preview
[img]
Preview
Image
Atkinson_Figure3.tif - Accepted version

Download (26MB) | Preview
[img]
Preview
Image
Atkinson_Figure4_R1_new.tif - Accepted version

Download (26MB) | Preview
[img]
Preview
Image
Atkinson_Figure5_v2b.tif - Accepted version

Download (26MB) | Preview
[img]
Preview
Image
Atkinson_Figure6.tif - Accepted version

Download (26MB) | Preview

Abstract

Purpose To create a high temporal- and spatial-resolution retrospectively cardiac-gated, tissue phase mapping (TPM) sequence, using an image-based respiratory navigator calculated from the data itself. Methods The sequence was based on a golden-angle spiral acquisition. Reconstruction of real-time images allowed creation of an image-based navigator. The expiratory spiral interleaves were then retrospectively cardiac-gated using data binning. TPM data were acquired in 20 healthy volunteers and 10 patients with pulmonary hypertension. Longitudinal and radial myocardial velocities were calculated in the left ventricle and right ventricle. Results The image-based navigator was shown to correlate well with simultaneously acquired airflow data in 10 volunteers(r=0.93±0.04). The TPM navigated images had a significantly higher subjective image quality and edge sharpness (P<0.0001) than averaged spiral TPM. No significant differences in myocardial velocities were seen between conventional Cartesian TPM with navigator respiratory-gating and the proposed self-navigated TPM technique, in 10 volunteers. Significant differences in the velocities were seen between the volunteers and patients in the left ventricle at systole and end diastole and in the right ventricle at end diastole. Conclusion The feasibility of measuring myocardial motion using a golden-angle spiral TPM sequence was demonstrated, with an image-based respiratory navigator calculated from the TPM data itself.

Type: Article
Title: Self-Navigated Tissue Phase Mapping Using a Golden-Angle Spiral Acquisition-Proof of Concept in Patients with Pulmonary Hypertension
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/mrm.24646
Publisher version: https://doi.org/10.1002/mrm.24646
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Science & Technology, Life Sciences & Biomedicine, Radiology, Nuclear Medicine & Medical Imaging, RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING, tissue phase mapping, myocardial motion, golden-angle, image-based self-navigation, TEMPORAL-RESOLUTION, MYOCARDIAL MOTION, CONTRAST MR, ARTERIAL-HYPERTENSION, RECONSTRUCTION, VOLUNTEERS, IMAGES, FLOW, DYSSYNCHRONY, ORDER
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Metabolism and Experi Therapeutics
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Childrens Cardiovascular Disease
URI: https://discovery.ucl.ac.uk/id/eprint/1385907
Downloads since deposit
63Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item