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Do children with uncomplicated severe acute malnutrition need antibiotics? A systematic review and meta-analysis.

Alcoba, G; Kerac, M; Breysse, S; Salpeteur, C; Galetto-Lacour, A; Briend, A; Gervaix, A; (2013) Do children with uncomplicated severe acute malnutrition need antibiotics? A systematic review and meta-analysis. PLoS One , 8 (1) , Article e53184. 10.1371/journal.pone.0053184. Green open access

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Abstract

Current (1999) World Health Organization guidelines recommend giving routine antibiotics (AB) for all children with severe acute malnutrition (SAM), even if they have uncomplicated disease with no clinically obvious infections. We examined the evidence behind this recommendation.

Type: Article
Title: Do children with uncomplicated severe acute malnutrition need antibiotics? A systematic review and meta-analysis.
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1371/journal.pone.0053184
Publisher version: http://dx.doi.org/10.1371/journal.pone.0053184
Language: English
Additional information: © 2013 Alcoba et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. GA started this review as part of his self-funded MSc in Public Health (MPH) in Developing Countries at the London School of Hygiene and Tropical Medicine, and was funded in 2009 by Action Contre la Faim to conduct this review with the co-authors. Since 2010, GA is funded by the Geneva University Hospital, Child and Adolescent Department, where the full review and manuscript have been completed, under the supervision of AG, a paediatric infectious diseases specialist. The other authors did not receive any specific funding for this review. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
UCL classification: UCL
URI: https://discovery.ucl.ac.uk/id/eprint/1384418
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