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Adverse drug reactions in children--a systematic review.

Smyth, RM; Gargon, E; Kirkham, J; Cresswell, L; Golder, S; Smyth, R; Williamson, P; (2012) Adverse drug reactions in children--a systematic review. PLOS One , 7 (3) , Article e24061. 10.1371/journal.pone.0024061. Green open access

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Abstract

Adverse drug reactions in children are an important public health problem. We have undertaken a systematic review of observational studies in children in three settings: causing admission to hospital, occurring during hospital stay and occurring in the community. We were particularly interested in understanding how ADRs might be better detected, assessed and avoided.

Type: Article
Title: Adverse drug reactions in children--a systematic review.
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1371/journal.pone.0024061
Publisher version: http://dx.doi.org/10.1371/journal.pone.0024061
Language: English
Additional information: © 2012 Smyth et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. This work was funded by the National Institute of Health Research (NIHR) working in collaboration with the University of Liverpool and Alder Hey Children's NHS Foundation Trust (reference number: RP-PG-0606-1170). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Keywords: Child, Drug Toxicity, Hospitalization, Humans, Outpatients
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Infection, Immunity and Inflammation Dept
URI: https://discovery.ucl.ac.uk/id/eprint/1375461
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