UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

STRUCTURE OF A PLATINUM(II) COMPLEX OF 1-BETA-D-ARABINOFURANOSYL)CYTOSINE

NEIDLE, S; TAYLOR, G; ROBINS, A; (1978) STRUCTURE OF A PLATINUM(II) COMPLEX OF 1-BETA-D-ARABINOFURANOSYL)CYTOSINE. ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE , 34 (Part 6) 1838 - 1841. 10.1107/S0567740878006792. Green open access

[img]
Preview
PDF
a16140.pdf
Available under License : See the attached licence file.

Download (403kB)

Abstract

The structure of a complex, arapen, formed between Pt ethylenediamine dichloride (PtenCl 2) and 1-(fl-Darabinofuranosyl) cytosine (ara-C) is described. The sugar puckering is C(2')-endo, and an intramolecular hydrogen bond connecting 0(2') to 0(5') in the sugar moiety is observed, a feature seen in the structure of neutral ara-C. The possible implications of the structure to reactivity studies of the complex with nucleic acid components are discussed. [Crystal data: (CI~H2~NsOsPtCI)+CI -, space group P21212, a = 24.440 (2), b = 10.388 (2), c = 6.700 (1) ,/~, Z = 4.]

Type: Article
Title: STRUCTURE OF A PLATINUM(II) COMPLEX OF 1-BETA-D-ARABINOFURANOSYL)CYTOSINE
Open access status: An open access version is available from UCL Discovery
DOI: 10.1107/S0567740878006792
Publisher version: http://scripts.iucr.org/cgi-bin/paper?S05677408780...
Language: English
Additional information: Copyright © International Union of Crystallography
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy
URI: https://discovery.ucl.ac.uk/id/eprint/1367871
Downloads since deposit
72Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item