Kortenkamp, A;
Faust, M;
Scholze, M;
Backhaus, T;
(2007)
Low-level exposure to multiple chemicals: reason for human health concerns?
Environmental Health Perspectives
, 115
(Suppl )
106 - 114.
10.1289/ehp.9358.
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Abstract
The widely held view that mixtures of dissimilarly acting chemicals are "safe" at levels below NOAELs is not supported by empirical evidence. We show that this view is also based on the erroneous assumption that NOAELs can be equated with zero-effect levels. Thus, on the basis of published evidence, it is difficult to rule out the possibility of mixture effects from low-dose multiple exposures.
| Type: | Article |
|---|---|
| Title: | Low-level exposure to multiple chemicals: reason for human health concerns? |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1289/ehp.9358 |
| Publisher version: | http://dx.doi.org/10.1289/ehp.9358 |
| Language: | English |
| Keywords: | dose addition, independent action, low dose, mixture toxicity, multiple exposures, risk assessment |
| UCL classification: | UCL |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1363921 |
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