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Joint Registration and Limited-Angle Reconstruction of Digital Breast Tomosynthesis

Yang, G; Hipwell, JH; Tanner, C; Hawkes, DJ; Arridge, SR; (2012) Joint Registration and Limited-Angle Reconstruction of Digital Breast Tomosynthesis. In: Maidment, ADA and Bakic, PR and Gavenonis, S, (eds.) Breast Imaging: 11th International Workshop, IWDM 2012, Philadelphia, PA, USA, July 8-11, 2012: Proceedings. (pp. 713 - 720). Springer-Verlag: Berlin / Heidelberg, Germany. Green open access

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Abstract

Digital breast tomosynthesis (DBT), an emerging imaging modality, provides a pseudo-3D image of the breast. Algorithms to aid the human observer process these large datasets involve two key tasks: reconstruction and registration. Previous studies separated these steps, solving each task independently. This can be effective if reconstructing using a complete set of data, e.g., in cone beam CT, assuming that only simple deformations exist. However, for ill-posed limited-angle problems such as DBT, estimating the deformation is complicated by the significant artefacts associated with DBT reconstructions, leading to severe inaccuracies in the registration. In this paper, we present an innovative algorithm, which combines reconstruction of a pair of temporal DBT acquisitions with their simultaneous registration. Using various computational phantoms and in vivo DBT simulations, we show that, compared to the conventional sequential method, jointly estimating image intensities and transformation parameters gives superior results with respect to reconstruction fidelity and registration accuracy.

Type: Proceedings paper
Title: Joint Registration and Limited-Angle Reconstruction of Digital Breast Tomosynthesis
ISBN-13: 9783642312700
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/978-3-642-31271-7_92
Publisher version: http://dx.doi.org/10.1007/978-3-642-31271-7_92
Language: English
Additional information: The original publication is available at www.springerlink.com
Keywords: Image reconstruction, Image registration, Digital breast tomosynthesis, Limited angle tomography, Inverse problem, Fully coupled optimisation, Decoupled approach
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/1356451
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