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Monitoring collagen gelling by elastic scattering spectroscopy (ESS)

Jawad, H; Austwick, M; MacRobert, S; Kuraishi, A; Tully, F; Alkseeva, T; Brown, R; (2011) Monitoring collagen gelling by elastic scattering spectroscopy (ESS). In: Abstracts of the Tissue and Cell Engineering Society (TCES) meeting 28-30 July 2010, University of Manchester. (pp. 52 - 52). Green open access

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Abstract

Collagen is being used extensively in tissue engineering and on a larger scale in the field of cosmetic surgery. It is either used as a gel or plastically compressed sheet. The fundamental science behind collagen gelling has been studied but little is known about the precise timing of gelling and the variables that affect gelling in the first 30 minutes. Critically, before collagen can be engineered as a predictable functional material we must be able to control fibril aggregation and gel formation. Here we report on the use of elastic scattering spectroscopy (ESS) to detect changes in scattering in rat tail and GMP bovine skin collagen during gelling. Effect of cell seeding on gelling is also reported.

Type: Proceedings paper
Title: Monitoring collagen gelling by elastic scattering spectroscopy (ESS)
Event: Tissue and Cell Engineering Society (TCES) meeting
Location: University of Manchester
Dates: 28 July 2010-30 July 2010
Open access status: An open access version is available from UCL Discovery
Publisher version: http://www.ecmjournal.org/journal/supplements/vol0...
Language: English
Additional information: Reproduced with kind permission from eCM journal (www.ecmjournal.org)
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Surgical Biotechnology
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of the Built Environment
URI: https://discovery.ucl.ac.uk/id/eprint/1354165
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