Goode, AE; Perkins, JM; Sandison, A; Karunakaran, C; Cheng, H; Wall, D; Skinner, JA; ... Ryan, MP; + view all Goode, AE; Perkins, JM; Sandison, A; Karunakaran, C; Cheng, H; Wall, D; Skinner, JA; Hart, AJ; Porter, AE; McComb, DW; Ryan, MP; - view fewer (2012) Chemical speciation of nanoparticles surrounding metal-on-metal hips. Chem Commun (Camb) , 48 (67) 8335 - 8337. 10.1039/c2cc33016d.

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Abstract

Spectromicroscopy of tissue surrounding failed CoCr metal-on-metal hip replacements detected corroded nanoscale debris in periprosthetic tissue in two chemical states, with concomitant mitochondrial damage. The majority of debris contained Cr(3+), with trace amounts of oxidised cobalt. A minority phase containing a core of metallic chromium and cobalt was also observed.

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