Raison, C;
Porter, S;
Fedele, S;
Lewis, MP;
Salih, V;
(2011)
Collagen gel as a 3D in vitro tissue model for ameloblastoma studies.
In:
Abstracts of the Tissue and Cell Engineering Society (TCES) meeting 28-30 July 2010, University of Manchester.
(pp. 86 - 86).
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Abstract
Ameloblastoma is a rare locally invasive epithelial odontogenic tumour of the jaw which can cause significant and debilitating bone destruction. In vitro studies of ameloblastoma are sparse in the literature, and little is known regarding patterns of ameloblastoma cell growth and invasion, as well as relevant gene and protein expression. This study aims to (i) use plastic-compressed collagen gels as a robust and relevant biomimetic to culture ameloblastoma cells in a 3D in vitro tissue model [1] and (ii) perform histology, immunohistochemistry (IHC) and gene expression assays to characterise tissue remodelling, cell growth and invasiveness.
Type: | Proceedings paper |
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Title: | Collagen gel as a 3D in vitro tissue model for ameloblastoma studies |
Event: | Tissue and Cell Engineering Society (TCES) meeting |
Location: | University of Manchester |
Dates: | 28 July 2010-30 July 2010 |
Open access status: | An open access version is available from UCL Discovery |
Publisher version: | http://www.ecmjournal.org/journal/supplements/vol0... |
Language: | English |
Additional information: | Reproduced with kind permission from eCM journal (www.ecmjournal.org) |
UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute |
URI: | https://discovery.ucl.ac.uk/id/eprint/1353089 |
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