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Biocompatible phosphate glass fibre scaffolds engineering of the hard/ soft tissue interface

Bitar, M; Knowles, JC; Salih, V; Lewis, MP; (2004) Biocompatible phosphate glass fibre scaffolds engineering of the hard/ soft tissue interface. In: Abstracts of eCells and Materials V The Cell Biomaterial Reaction 28th - 30th June 2004, Congress Centre, Davos, Switzerland. (pp. 26 - 26). Green open access

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Abstract

Phosphate based glasses maintain the survival, phenotype and morphology of adherent human bone and ligament cells (1) and may prove ideal, as scaffolding material, for tissue engineering dealing with ligament-tendon/ bone attachment defects. This work assesses the biocompatibility of fibre constructs of both, ternary (CaO–Na2O–P2O5) and Quaternary (iron containing) compositions as candidates for a contiguous osteoblast/ fibroblast seeded in vitro systems. This is achieved by firstly, identifying the optimum fibre diameter and secondly, comparing various glass compositions for biocompatibility through evaluating cell adhesion, proliferation and morphology.

Type: Proceedings paper
Title: Biocompatible phosphate glass fibre scaffolds engineering of the hard/ soft tissue interface
Event: The Cell Biomaterial Reaction
Location: Congress Centre, Davos, Switzerland
Dates: 28th June 2004- 30th June 2004
Open access status: An open access version is available from UCL Discovery
Publisher version: http://www.ecmjournal.org/journal/supplements/vol0...
Language: English
Additional information: Reproduced with kind permission from eCM journal (www.ecmjournal.org)
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute > Biomaterials and Tissue Eng
URI: https://discovery.ucl.ac.uk/id/eprint/1352725
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