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An assessment of the human nail plate pH.

Murdan, S; Milcovich, G; Goriparthi, GS; (2011) An assessment of the human nail plate pH. Skin Pharmacol Physiol , 24 (4) 175 - 181. 10.1159/000324055. Green open access

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Abstract

Purpose of Study: To measure the pH of the surface of healthy nail plates. Procedures: The surface pH of human fingernails and big toenails was measured in vivo using a skin pH meter. The influence of washing, anatomical site (fingers/toes), side (left/right), digit (digits 1–5) and gender was determined. The pH of the nail interior was also measured. Results: The pH of the nail plate surface was around 5, with toenails having a significantly higher pH than fingernails. Immediately after hand washing, the nail surface pH increased significantly, from pH 5.1 ± 0.4 to 5.3 ± 0.5. However, this was not sustained with time, and the pH returned to prewashing levels within 20 min. Gender had an influence on unwashed, but not washed, nail plate pH. The pH of the nail plate interior was lower than that of its surface. Conclusions: It was possible to measure nail plate pH, and baseline values are provided.

Type: Article
Title: An assessment of the human nail plate pH.
Location: Switzerland
Open access status: An open access version is available from UCL Discovery
DOI: 10.1159/000324055
Publisher version: http://dx.doi.org/10.1159/000324055
Language: English
Additional information: Copyright © 2011 S. Karger AG, Basel
Keywords: Adult, Aged, Female, Fingers, Humans, Hydrogen-Ion Concentration, Male, Middle Aged, Nails, Prospective Studies, Toes, Young Adult
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy > Pharmaceutics
URI: https://discovery.ucl.ac.uk/id/eprint/1351488
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