Shepherd, A;
Brown, R;
Bozec, L;
(2009)
Mimicking the body- a novel method of Cross-linking collagen to control scaffold design- implications on human tissue engineering.
In:
Abstracts of the Tissue and Cell Engineering Society (TCES) meeting 8-10 July 2009, Universities of Glasgow & Strathclyde.
(pp. 100 - 100).
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Abstract
Scaffold design is an essential part of tissue engineering. Cross-linked collagen matrices are often used to increase the mechanical strength of scaffolds. The ability to create and control different patterns of cross-linking within a collagen matrix would allow manipulation of scaffold characteristics (e.g. anisotropy, strength and shape) in order to tailor the design of the scaffold more appropriately to different applications. Photochemical crosslinking using Riboflavin and blue light1 has the potential to create patterns of crosslinking throughout a matrix. If successful, it can have applications in more sophisticated scaffold creation such as crosslinked tubular structures for nerve and vascular engineering. This study will assess the suitability of this method for such an application.
| Type: | Proceedings paper |
|---|---|
| Title: | Mimicking the body- a novel method of Cross-linking collagen to control scaffold design- implications on human tissue engineering |
| Event: | Tissue and Cell Engineering Society (TCES) meeting |
| Location: | Universities of Glasgow & Strathclyde |
| Dates: | 08 Jul 2009 - 10 Jul 2009 |
| Open access status: | An open access version is available from UCL Discovery |
| Publisher version: | http://www.ecmjournal.org/journal/supplements/vol0... |
| Language: | English |
| Additional information: | Reproduced with kind permission from eCM journal (www.ecmjournal.org) |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1348947 |
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