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Basement membrane protein orchestrates network formation by endothelial cells in 3D: Laminin the conductor

Stamati, K; Priestley, JV; Mudera, V; Cheema, U; (2011) Basement membrane protein orchestrates network formation by endothelial cells in 3D: Laminin the conductor. In: Abstracts of the Tissue and Cell Engineering Society (TCES) meeting 19-21 July 2011, University of Leeds. (pp. 7 - 7). Green open access

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Abstract

Engineering vascular networks within 3D tissue models is paramount for the survival of cells in large 3D constructs. This is critical for both in vitro and in vivo survival. Our work has focused on network formation by endothelial cells in co-cultures with Human bone marrow stromal cells (HBMSCs) in 3D. We have examined the effect of matrix composition on endothelial cell morphology and our results emphasize the importance of basement membrane proteins for inducing network formation by endothelial cells.

Type: Proceedings paper
Title: Basement membrane protein orchestrates network formation by endothelial cells in 3D: Laminin the conductor
Event: Tissue and Cell Engineering Society (TCES) meeting
Location: University of Leeds
Dates: 19/07/2011-21/07/2011
Open access status: An open access version is available from UCL Discovery
Publisher version: http://www.ecmjournal.org/journal/supplements/vol0...
Language: English
Additional information: Reproduced with kind permission from eCM journal (www.ecmjournal.org)
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Ortho and MSK Science
URI: https://discovery.ucl.ac.uk/id/eprint/1348475
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