UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Three-dimensional optical topography of brain activity in infants watching videos of human movement.

Correia, T; Lloyd-Fox, S; Everdell, N; Blasi, A; Elwell, C; Hebden, JC; Gibson, A; (2012) Three-dimensional optical topography of brain activity in infants watching videos of human movement. Physics in Medicine and Biology , 57 (5) , Article 1135. 10.1088/0031-9155/57/5/1135. Green open access

[img]
Preview
PDF
1340340.pdf
Available under License : See the attached licence file.

Download (589kB)

Abstract

We present 3D optical topography images reconstructed from data obtained previously while infants observed videos of adults making natural movements of their eyes and hands. The optical topography probe was placed over the temporal cortex, which in adults is responsible for cognitive processing of similar stimuli. Increases in oxyhaemoglobin were measured and reconstructed using a multispectral imaging algorithm with spatially variant regularization to optimize depth discrimination. The 3D optical topography images suggest that similar brain regions are activated in infants and adults. Images were presented showing the distribution of activation in a plane parallel to the surface, as well as changes in activation with depth. The time-course of activation was followed in the pixel which demonstrated the largest change, showing that changes could be measured with high temporal resolution. These results suggest that infants a few months old have regions which are specialized for reacting to human activity, and that these subtle changes can be effectively analysed using 3D optical topography.

Type: Article
Title: Three-dimensional optical topography of brain activity in infants watching videos of human movement.
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1088/0031-9155/57/5/1135
Publisher version: http://dx.doi.org/10.1088/0031-9155/57/5/1135
Language: English
Additional information: © 2012 Institute of Physics and IOP Publishing.
Keywords: Algorithms, Attention, Brain Mapping, Cohort Studies, Depth Perception, Female, Humans, Image Processing, Computer-Assisted, Imaging, Three-Dimensional, Infant, Movement, Optics and Photonics, Oxyhemoglobins, Temporal Lobe, Time Factors
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/1340340
Downloads since deposit
127Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item