UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Epileptic networks in focal cortical dysplasia revealed using electroencephalography-functional magnetic resonance imaging.

Thornton, R; Vulliemoz, S; Rodionov, R; Carmichael, DW; Chaudhary, UJ; Diehl, B; Laufs, H; ... Lemieux, L; + view all (2011) Epileptic networks in focal cortical dysplasia revealed using electroencephalography-functional magnetic resonance imaging. Annals of Neurology , 70 (5) 822 - 837. 10.1002/ana.22535. Green open access

[thumbnail of 1334368.pdf]
Preview
PDF
1334368.pdf

Download (436kB)

Abstract

Surgical treatment of focal epilepsy in patients with focal cortical dysplasia (FCD) is most successful if all epileptogenic tissue is resected. This may not be evident on structural magnetic resonance imaging (MRI), so intracranial electroencephalography (icEEG) is needed to delineate the seizure onset zone (SOZ). EEG-functional MRI (fMRI) can reveal interictal discharge (IED)-related hemodynamic changes in the irritative zone (IZ). We assessed the value of EEG-fMRI in patients with FCD-associated focal epilepsy by examining the relationship between IED-related hemodynamic changes, icEEG findings, and postoperative outcome.

Type: Article
Title: Epileptic networks in focal cortical dysplasia revealed using electroencephalography-functional magnetic resonance imaging.
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1002/ana.22535
Publisher version: http://dx.doi.org/10.1002/ana.22535
Language: English
Additional information: This work is made available under a Creative Commons license. PMCID: PMC3500670
Keywords: Adult, Brain, Electroencephalography, Epilepsies, Partial, Female, Follow-Up Studies, Humans, Magnetic Resonance Imaging, Male, Malformations of Cortical Development, Middle Aged, Neural Pathways, Patient Discharge, Postoperative Period, Preoperative Period, Treatment Outcome
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Experimental Epilepsy
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
URI: https://discovery.ucl.ac.uk/id/eprint/1334368
Downloads since deposit
131Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item