Thornton, R;
Vulliemoz, S;
Rodionov, R;
Carmichael, DW;
Chaudhary, UJ;
Diehl, B;
Laufs, H;
... Lemieux, L; + view all
(2011)
Epileptic networks in focal cortical dysplasia revealed using electroencephalography-functional magnetic resonance imaging.
Annals of Neurology
, 70
(5)
822 - 837.
10.1002/ana.22535.
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Abstract
Surgical treatment of focal epilepsy in patients with focal cortical dysplasia (FCD) is most successful if all epileptogenic tissue is resected. This may not be evident on structural magnetic resonance imaging (MRI), so intracranial electroencephalography (icEEG) is needed to delineate the seizure onset zone (SOZ). EEG-functional MRI (fMRI) can reveal interictal discharge (IED)-related hemodynamic changes in the irritative zone (IZ). We assessed the value of EEG-fMRI in patients with FCD-associated focal epilepsy by examining the relationship between IED-related hemodynamic changes, icEEG findings, and postoperative outcome.
| Type: | Article |
|---|---|
| Title: | Epileptic networks in focal cortical dysplasia revealed using electroencephalography-functional magnetic resonance imaging. |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1002/ana.22535 |
| Publisher version: | http://dx.doi.org/10.1002/ana.22535 |
| Language: | English |
| Additional information: | This work is made available under a Creative Commons license. PMCID: PMC3500670 |
| Keywords: | Adult, Brain, Electroencephalography, Epilepsies, Partial, Female, Follow-Up Studies, Humans, Magnetic Resonance Imaging, Male, Malformations of Cortical Development, Middle Aged, Neural Pathways, Patient Discharge, Postoperative Period, Preoperative Period, Treatment Outcome |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Experimental Epilepsy UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1334368 |
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