UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Measurement and analysis of brain deformation during neurosurgery.

Hartkens, T; Hill, DLG; Castellano-Smith, AD; Hawkes, DJ; Maurer, CR; Martin, AJ; Hall, WA; ... Truwit, CL; + view all (2003) Measurement and analysis of brain deformation during neurosurgery. IEEE Trans Med Imaging , 22 (1) pp. 82-92. 10.1109/TMI.2002.806596. Green open access

[img]
Preview
PDF
13341.pdf

Download (1MB)

Abstract

Recent studies have shown that the surface of the brain is deformed by up to 20 mm after the skull is opened during neurosurgery, which could lead to substantial error in commercial image-guided surgery systems. We quantitatively analyze the intraoperative brain deformation of 24 subjects to investigate whether simple rules can describe or predict the deformation. Interventional magnetic resonance images acquired at the start and end of the procedure are registered nonrigidly to obtain deformation values throughout the brain. Deformation patterns are investigated quantitatively with respect to the location and magnitude of deformation, and to the distribution and principal direction of the displacements. We also measure the volume change of the lateral ventricles by manual segmentation. Our study indicates that brain shift occurs predominantly in the hemisphere ipsi-lateral to the craniotomy, and that there is more brain deformation during resection procedures than during biopsy or functional procedures. However, the brain deformation patterns are extremely complex in this group of subjects. This paper quantitatively demonstrates that brain deformation occurs not only at the surface, but also in deeper brain structure, and that the principal direction of displacement does not always correspond with the direction of gravity. Therefore, simple computational algorithms that utilize limited intraoperative information (e.g., brain surface shift) will not always accurately predict brain deformation at the lesion.

Type: Article
Title: Measurement and analysis of brain deformation during neurosurgery.
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1109/TMI.2002.806596
Keywords: Adult, Aged, Aged, 80 and over, Algorithms, Brain, Brain Diseases, Cerebral Ventricles, Child, Preschool, Craniotomy, Female, Humans, Image Enhancement, Image Interpretation, Computer-Assisted, Magnetic Resonance Imaging, Male, Middle Aged, Models, Biological, Monitoring, Intraoperative, Motion, Reproducibility of Results, Sensitivity and Specificity, Subtraction Technique, Surgery, Computer-Assisted
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/13341
Downloads since deposit
555Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item