Padidela, R;
Bryan, SM;
Abu-Amero, S;
Hudson-Davies, RE;
Achermann, JC;
Moore, GE;
Hindmarsh, PC;
(2012)
The growth hormone receptor gene deleted for exon three (GHRd3) polymorphism is associated with birth and placental weight.
Clinical Endocrinology
, 76
(2)
236 - 240.
10.1111/j.1365-2265.2011.04207.x.
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Abstract
Human growth hormone receptor (GHR) transcripts have two isoforms, full-length (GHRfl) or exon 3 deleted (GHRd3). An association of these isoforms has been found with small for gestational age (SGA) infants but does not influence adult height. The role of this polymorphism in the birth size spectrum in the general population is unclear.
| Type: | Article |
|---|---|
| Title: | The growth hormone receptor gene deleted for exon three (GHRd3) polymorphism is associated with birth and placental weight. |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1111/j.1365-2265.2011.04207.x |
| Publisher version: | http://dx.doi.org/10.1111/j.1365-2265.2011.04207.x |
| Language: | English |
| Additional information: | © 2011 Blackwell Publishing Ltd. Re-use of this article is permitted in accordance with the Terms and Conditions set out at http://wileyonlinelibrary.com/onlineopen# OnlineOpen_Terms. PMCID: PMC3321225 |
| Keywords: | Birth Weight, Exons, Female, Fetal Development, Gene Deletion, Genotype, Humans, Organ Size, Placenta, Polymorphism, Genetic, Pregnancy, Receptors, Somatotropin |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Genetics and Genomic Medicine Dept |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1323016 |
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